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KMID : 0382420030290020007
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Korean Journal of Environmental Health Society
2003 Volume.29 No. 2 p.7 ~ p.15
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Study on Anti-estrogenic Activity of DEHP as an Endocrine Disruption Chemical
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Kim Eun-Joo
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Abstract
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Di-2-ethylhexyl phthalate (DEHP). is a widely used plasticizer known to be a suspected endocrine disrupter. but its exact effects on aquatic organisms are not yet known. When Japanese medaka (Oryzias latipes) were exposed from the time of hatching to 3 months of age to an aqueous DEHP solution at nominal concentrations of I. 10. and 50 ㎍//. DEHP treated female fish showed distinct reproductive effects. And the midge (Chironomus riparius). an aquatic invertebrate. was exposed to DEHP to evaluate the effects on reproductive processes via sediment toxicity. The test endpoints included emergence. sex ratio, fecundity. and the viability of FI offspring egg ropes. The result implied that the normal developmental and/or reproductive processes in C. riparius had been disrupted when exposed to DEHP. the effect also being displayed in the next generation. In summary. DEHP hinders the development of reproductive organs in the female Japanese medaka and C. riparius.
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